What you need to know about hyaluronic acid injections? Contraindications to the introduction of hyaluronic acid Is it harmful to do injections of hyaluronic acid

Features of the impact hyaluronic acid on the skin

Hyaluronic acid (HA) is a naturally occurring polysaccharide substance that is present from birth in the body of every person and regulates water balance in the tissues. She is directly involved in the production of elastin and collagen, which are responsible for the elasticity and youth of the skin.

At a young age, hyaluronate is actively synthesized by the body itself, so the girl's skin always looks nourished, smooth, elastic. But with age, the production of its own substance slows down, tissues begin to quickly lose moisture, and the skin loses its tone, dries up, and small wrinkles appear on it.

The modern beauty industry, which stands guard over female beauty, has found a great way to keep beautiful ladies young. Today, synthetic hyaluronic acid is widely used in cosmetic anti-aging products and youth injections. Cosmetologists offer several types of beauty injections, from which a suitable procedure is selected, taking into account certain problems on the skin of the face:

1. Mesotherapy - a procedure for the youngest girls from 23 to 30 years old. It involves the injection of hyaluronate under the skin in combination with other beneficial substances. Mesotherapy allows you to improve complexion, remove pigmentation, increase tone, eliminate flabbiness and the first manifestations of wrinkles. For the best effect, it is necessary to carry out several procedures that give a cumulative effect. Visible result appears after the second visit to the beautician.

2. Biorevitalization - a procedure that is suitable for women over 40. The main component of the injections is hyaluronate. After the very first visit to a specialist deep wrinkles are smoothed, the skin is tightened, becomes elastic, nourished.

3. Fillers - point injections of hyaluronic acid for the face. For this, hyaluronan of high density and viscosity without additional impurities is used, which fills in folds and wrinkles. With the help of such manipulations, specialists can correct the shape of the lips, nose, and correct the shape of the face.

But you should not rush into the whirlpool with your head, but you need to thoroughly understand all the pros and cons of injection procedures with HA.

Useful properties of hyaluronic acid for facial skin

Hyaluronan has undeniable benefits for the beauty of facial skin. Its main properties:

  • maintains the amount of moisture in the intercellular space;
  • eliminates flabbiness;
  • evens out skin tone;
  • eliminates pigmentation, helps to fight acne and the marks after it;
  • evens out the skin relief, provides smoothness;
  • has an anti-inflammatory effect and accelerates tissue regeneration, promotes rapid healing of scratches, burns;
  • gives clearer contours to the face;
  • normalizes blood circulation and sebaceous glands.

Hyaluronic injections are called a real rejuvenating elixir. But is everything so cloudless? Consider reverse side medals.

What harm can hyaluronic injections do for the face?

When used correctly and professionally, HA usually does not cause side effects. Qualified cosmetologists always carry out preliminary testing of clients' skin, identifying possible contraindications. About a tendency to allergies or chronic
diseases must always be reported to a specialist in advance.

One of the most unpleasant consequences of regular beauty injections with hyaluronate is addiction, as a result of which the skin practically stops synthesizing its own substance. The effect of hyaluronic acid lasts about 1 year, and when the injections are canceled, the skin quickly loses its tone and elasticity. Therefore, women who decide to take such a step should think carefully about whether they are ready for regular visits to a beautician.

Other side effects of the procedures:

  • the appearance of bruises or bumps on the face;
  • swelling;
  • irritation, redness of the skin.

Such consequences usually go away on their own within a few days. To achieve maximum effect from the internal administration of HA, it is necessary to consume at least one and a half liters of pure water daily, otherwise you can get the exact opposite result - excessive dryness skin.

Contraindications for use

The benefits of hyaluronic acid injections are certainly high, but there are some restrictions under which procedures are prohibited. The absolute contraindications include:

  • chronic diseases during an exacerbation;
  • infectious diseases accompanied by fever;
  • During pregnancy and breastfeeding;
  • oncological neoplasms;
  • inflammation of the skin, papillomas, dermatitis, boils, ulcerative wounds.

The injection of youth is not worth it spend for 30 days after other procedures of deep influence on the skin - laser resurfacing, photorejuvenation, and acid peels.

In contact with

Hyaluronic acid is most often used in cosmetology, but it can solve the problem of diseased joints, when the amount of synovial fluid in them decreases and cartilage deformities develop. Often, doctors recommend that their patients take a course of pills with hyaluronic acid. The benefits of drugs:

  • there is a beneficial effect on the entire body;
  • first, hyaluronic acid begins to saturate the joint fluid and only after that it penetrates the cells of the dermis;
  • improves vision, acid helps with increased eye fatigue, temporary presence dark spots and "flies";
  • the skin is rejuvenated, but this effect occurs only after 3 months of regular intake of the drug;
  • mental activity improves and endurance increases.

Precautionary measures:

  • it is not known how an excess of hyaluronic acid affects the functionality of organs and systems, so it is not worth taking it before the age of 25;
  • if you drink for too long, then a problem of weight gain may appear, since the main active substance belongs to polysaccharides and in the stomach simply breaks down into sugars that are harmful to the figure;
  • the tablets may contain additional components and substances to change the taste, and they can provoke an acute allergic reaction.

Hyaluronic acid molecules work in the body exclusively at the cellular level, which leads not only to saturation of the dermis with moisture and an improvement in the structure and composition of the synovial fluid (located in the joints), but also stimulates, makes the processes of natural collagen and elastin production faster.

Only if the course of admission is 1 month or more, positive results can be expected... Doctors consider these products to be dietary supplements and strongly doubt their effectiveness.

Indications for oral administration:

  • spine diseases;
  • dry eye syndrome;
  • changes in the musculoskeletal system associated with the person's age;
  • diagnosed arthrosis (at the initial stage of its development);

Doctors never use hyaluronic acid tablets as the main therapeutic agent. Rather, it is an additional help to the body.

Contraindications for use:

  • acute course of an infectious disease;
  • inflammatory processes, regardless of their location;

General recommendation for taking medications: 1 tablet or capsule 3 times a day for at least 30 days. But you need to take into account the level of content in the preparation of the main active substance. Some manufacturers indicate the presence of 150 mg of hyaluronic acid in one tablet, others are limited to 70 mg. In the second case, you will need to adjust the dosage. Take 2 tablets or capsules three times a day.


Hyaluronic acid in liquid form, in tablets and capsules

Often, taking pills is combined with the use of drugs that contain collagen and the Q10 enzyme. Doctors recommend alternating the reception of such funds, in which case the maximum rejuvenating and strengthening effect will be provided.

For better absorption, the tablet must be held in the mouth and dissolve until a soft, jelly-like mass is formed.

Hyaluronic acid can be prescribed by doctors for eye diseases, including the destruction of the vitreous, but only if 2 conditions are met:

Self-administration of drugs with such a diagnosis is strictly prohibited.

On the whole, there is a lot of controversy about the appropriateness of admission. It should be understood that the substance, under the influence of gastric juice, breaks down into sugars and too little hyaluron gets to the cells of the organs. It is much more effective to choose a therapy regimen that involves injecting drugs.

Consumers themselves note that after 1-2 months of taking drugs for the better the skin changes, the joints begin to work easier, without squeaking and crunching.

Review of the most popular drugs:

"Laura"

Produced by the pharmaceutical company "Evalar", it is a multicomponent composition. In addition to the active substance, the tablets contain vitamin C, wild yam extract, peptides, vitamin E, phospholipids. BAA "Laura" rejuvenates the entire body, strengthening its immune system and renewing the skin.

Tablets are taken 1 piece 3 times a day directly with meals. The course of therapy is 30 days, after which it is worth taking a break for 1 month and repeating the manipulation. The cost of dietary supplements is not more than 300 rubles.

It is believed that pills with hyaluronic acid do not harm the body, but doctors warn:

  • it is not known how an excess of hyaluronic acid affects the functionality of organs and systems, so you should not take them before the age of 25;
  • if you take the pills for too long, then the problem of weight gain may appear, since the main active substance belongs to polysaccharides and in the stomach simply breaks down into sugars, which are clearly harmful to the figure;
  • additional components and even taste enhancers may be present in the composition of the tablets, and they are allergenic substances and can provoke an acute allergic reaction.

In any case, before undergoing a course of therapy with hyaluronic acid tablets, it is necessary to consult a doctor and make sure that this will be beneficial to health.

Indications for oral administration

Taking hyaluronic acid inside just like that, for general health and prevention is not worth it. There are a number of clear indications for such therapy:

  • excessively dry skin of the face and body;
  • the presence of small mimic wrinkles;
  • spine diseases;
  • dry eye syndrome;
  • recovery period after deep peeling;
  • changes in the musculoskeletal system associated with a person's age;
  • diagnosed arthrosis at the initial stage of its development;
  • rehabilitation after eye surgery.

Doctors never use hyaluronic acid tablets as the main therapeutic agent. Rather, it is an additional help to the body, which will speed up the process of general recovery.

Contraindications for use

  • periods of gestation and breastfeeding;
  • acute course of the infectious process;
  • inflammatory processes regardless of their location;
  • autoimmune diseases;
  • too fast blood clotting;
  • taking certain medications on a continuous basis;
  • allergy to the components that make up the product.

The described health features require prior consultation with a doctor about the advisability of a course of therapy with tablets with hyaluronic acid.

How to take hyaluronic acid capsules

The general recommendation for taking medications is 1 tablet or capsule 3 times a day for at least 30 days. But you need to take into account the level of content in the preparation of the main active substance. Some manufacturers indicate the presence of 150 mg of hyaluronic acid in one tablet, others are limited to 70 mg. In the second case, you will need to adjust the dosage. Take 2 tablets or capsules three times a day. The duration of the course does not change.

Often, taking pills is combined with the use of drugs that contain collagen and the Q10 enzyme. Doctors recommend alternating the reception of such funds, in which case the maximum rejuvenating and strengthening effect will be provided.

For better absorption, the tablet must be held in the mouth and dissolve until a soft, jelly-like mass is formed.

Will it help with the destruction of the vitreous

Since tablets with hyaluronic acid are recognized as a conventional dietary supplement, they should be considered as a complete medicinal product not worth it. They can be prescribed by doctors for eye diseases, including destruction of the vitreous body, but only if 2 conditions are met:

  • pathology is at an early stage of its development;
  • tablets act as an additional strengthening agent and nothing more.

Does it make sense to take hyaluronic acid internally at all?

If you answer in monosyllables, then practically no. The fact is that this substance, under the influence of gastric juice, breaks down into sugars and too little hyaluron gets to the cells of the organs. It is much more effective to choose a therapy regimen that involves injecting drugs.

There is also another opinion. The consumers themselves note that after 1-2 months of taking the drugs, the skin changes for the better, becoming smoother, more moisturized, the joints begin to work more easily, without squeaking and crunching.

Review of the most popular drugs

Among the variety of tablets with hyaluronic acid, experts identify only a few of the most effective:

BAA "Laura"

Produced by the pharmaceutical company "Evalar" and is a multicomponent composition. In addition to the active substance, the tablets contain vitamin C, wild yam extract, peptides, vitamin E, phospholipids. The dietary supplement rejuvenates the entire body, strengthening its immune system and making the skin smoother and well hydrated.

Laura tablets with hyaluronic acid are taken 1 piece 3 times a day directly with meals. The course of therapy is 30 days, after which it is worth taking a break for 1 month and repeating the manipulation. The cost of dietary supplements is no more than 300 rubles.

"Нyaluronic acid" from "Solgar"

A drug in which hyaluronic acid and collagen are successfully combined, and magnesium stearate, vitamin C, chondroitin sulfate and glycerin act as additional ingredients.

One capsule contains 120 mg of the main active ingredient, it will be enough to take 1 piece 1 time per day. The duration of the course of therapy is at least a month, the cost of the drug is 2000 rubles for 30 capsules.

A significant drawback of the "Solgar" preparation is that the capsule is too large, which makes it problematic to swallow it.

"KWC"

This is a dietary supplement made in Japan, which also contains vitamins and minerals. The manufacturer claims that it is his drug that has a general anti-aging effect, which leads to an improvement in the condition of the skin, vision, increased joint performance and strengthening of immunity.

The cost of the drug is high - about 3,500 rubles for 30 capsules. Take 1 piece per day for a month.

Taking hyaluronic acid inside is a very dubious therapy, but it can be carried out not with a therapeutic, but with a preventive or general strengthening purpose. There will still be positive results, but they will become noticeable only after a month from the start of taking the pills or capsules.

Useful video

See in this video about whether it makes sense to take hyaluronic acid internally:

There is no perfect method of rejuvenation, each has its own pros and cons. Not every method is suitable for a particular woman. There are contraindications to hyaluronic acid, although this substance is produced in the human body and is not alien to it. Therefore, you should carefully approach the choice of the procedure and the drug for it. The final result depends on this.

How is hyaluronic acid useful?

This compound is part of the intercellular fluid. Its amount depends on the age of the person and the condition of the skin. The older a woman is, the less hyaluronic acid her body produces. For this reason, the face becomes dull, peeling and wrinkles appear.

Modern technologies make it possible to synthesize hyaluronic acid, which will repeat the properties of natural. At the same time, due to its artificial origin, it practically does not cause allergic reactions. The action of this substance can be described in several points:

  • increases the turgor of the dermis;
  • deeply moisturizes at the cell level;
  • reduces the number and severity of wrinkles;
  • improves the secretion of sebum (sebum);
  • tightens the contours of the face;
  • improves blood microcirculation;
  • helps to eliminate inflammation;
  • smoothes scars, making them less visible;
  • brightens hyperpigmentation;
  • allows you to make areas of the face or its individual parts (nose, lips, eyes) symmetrical;
  • gives the face clearer features by injecting the substance into the cheekbones;
  • corrects the shape and volume of lips when filling them;
  • fills in the nasolabial folds;
  • allows you to remove the signs of aging from your hands;
  • restores joint mobility in case of damage;
  • helps to restore the skin after burns and massive surgical interventions.

Not everyone can pay for services in a cosmetology salon. But there is a way to use hyaluronic acid at home. The effectiveness of the procedures will be noticeably lower, but it will still have a beneficial effect. This method of administration will help:

  • increase collagen production;
  • start regenerative processes;
  • deeply moisturize the skin;
  • even out the tone of the face;
  • smooth out fine wrinkles.

For home use you need to take a solution or powder of sodium hyaluronate, which is sold in ampoules. To 2 g of the drug, add 30 ml of purified water (boiled or distilled). Leave the mixture for 30 minutes, letting it swell. If after using the mask there is a large number of funds, it can be frozen for subsequent procedures. You can also inject acid using a mesoscooter. It is an effective alternative to salon care.

After the procedure, it is better to fix the result with an anti-aging serum, and then with a cream. This will strengthen beneficial features preparation and achieve the best result. But the effect at home is not carried out in the area of ​​the eyes, therefore, in this way it is impossible or hyperpigmentation in this area.

Is hyaluronic acid harmful

When using hyaluronic acid in persons prone to allergies, adverse reactions may occur. This substance, when properly administered, is not capable of harm to the rest of people. But, if safety precautions are not followed and procedures are repeated too often, negative consequences may occur.

These include a decrease in the synthesis of hyaluronic acid by the body itself. Such people have to inject the drug constantly, since without it the skin looks flabby and tired. To avoid this, you need to follow the doctor's recommendations on the frequency of injections.

Contraindications for use

There are several situations in which it is not recommended to use hyaluronic acid for any purpose. These conditions include:

  • period breastfeeding and pregnancy (due to the lack of reliable data, confirmed by scientific studies, about safety when used in women in this condition);
  • the presence of autoimmune pathologies;
  • iron deficiency in the blood;
  • allergy to hyaluronic acid or other components of the funds;
  • diseases accompanied by blood clotting disorders;
  • the presence of oncology of any localization;
  • diabetes;
  • the presence of an inflammatory process in the body;
  • peptic ulcer or gastritis are taken into account when prescribing drugs in the form of tablets (an acidic environment will increase the susceptibility of organs to inflammation);
  • any manifestations of dermatological pathologies;
  • the presence of an infectious process in the body, including colds.

If a person has recently undergone a course of deep peeling, laser action on the skin or hardware rejuvenation techniques, then it is better to postpone procedures with hyaluronic acid. Almost all bans on the use of these drugs are valid for a certain period of time, after which the funds are allowed to be used.

Risks of intradermal administration

There are risks associated with the use of hyaluronic acid intradermally. Therefore, it has a number of limitations:

  • age up to 25 years (it is not recommended to use it too early because of the possibility of reducing the natural synthesis of a substance in cells);
  • the presence of pustular and other inflammatory skin diseases (infection may spread throughout the body due to injury);
  • tendency to form keloid scars (increase the risk of visible complications from the procedure).

The introduction of hyaluronic acid into the skin is carried out using mesotherapy techniques. These include biorevitalization, which is less traumatic, but its effect also disappears faster. It is possible to use anti-aging agents in this way only for aging skin. For a younger person, less deep, non-invasive options are suitable.

Pros and cons of oral administration

The use of pills and capsules with hyaluronic acid has both benefits and harm. Side effects are especially pronounced when drinking a small amount of water. Therefore, it is necessary to drink from 1.5 liters or more in order to prevent skin dehydration and the appearance of peeling.

The negative effect from oral administration also arises from the additional components in the composition of the tablets. For this reason, preference should be given to proven products from well-known manufacturers. The use of hyaluronic acid inside is especially important for pathologies of the musculoskeletal system (bones and joints).

External use

The use of hyaluronic acid externally is possible only when the compound is decomposed into small molecules. This makes it available for skin penetration. In this way, it is possible to restore the epidermis after burns and wounds. It is also used to remove residual changes after dermatitis and other diseases that can leave scars and scars.

In some cases, hyaluronic acid gel is used to treat joint pathologies. It must be smeared on the affected area at least 3 times a day. In this case, external use is allowed during pregnancy, since the drugs do not penetrate into the blood. Feeding a newborn baby is also not dangerous if you do not apply funds to the breast.

External application is not used in the presence of skin lesions or neoplasms, since hyaluronic acid is able to trigger the synthesis of new cells. Due to this, the cancer process will accelerate. Therefore, you should check the nature of all moles in the area of ​​exposure to the drug before use.

Addiction risk

Intradermal hyaluronic acid injections can be habit-forming. This is due to the fact that the cells that produce it (fibroblasts) stop producing their own substance, since it comes from the outside in an amount sufficient to maintain the normal state of the body. Therefore, its use for young skin is highly discouraged.

In order to avoid the development of a side effect, doctors advise to inject the agent no more than once a year. In the presence of pronounced age-related changes, you can alternate procedures with the introduction of Botox. This will reduce the risk of side effects from both drugs.

Negative consequences

Complications may occur if the drug is misused or administered. They are especially often manifested with injections of hyaluronic acid, and external application is the safest. Side effects can usually be observed:

  • edema;
  • bruising at the injection site;
  • redness.

Hematomas are more likely to occur in smokers due to increased blood clotting. The face can swell from the use of certain brands of drugs. This is due to the presence of a stabilizer in their composition. And thin skin with a close location of capillaries is prone to redness.

These phenomena are not considered hazardous. They go away on their own 2-4 days after the procedure. Leech ointments can be applied to bruises to help them heal faster. Cool compresses help against swelling, but they need to be kept for no more than 5 minutes.

Unsuccessful administration of the drug can cause a dangerous side effect - tissue fibrosis. It forms at the injection site through which the filler was injected. You can determine its presence by touch or on examination: there is a seal and swelling.

Fibrous changes in tissues are subject to surgical removal. The reason for their appearance is individual reactions to the drug, the use of a bad filler or its illiterate introduction, when the agent enters the upper layers of the skin and crumples in them, overgrowing with connective fiber and continuing to swell. If you suspect this pathology, you should contact the doctor who performed the procedure, or the surgeon.

Side effects are not always the fault of the beautician. Often the reason is the failure to follow the doctor's recommendations. These situations include:

  • frequent or prolonged sun exposure without protective cream and headgear with brim, especially in summer;
  • hiding from the doctor restrictions on the use of hyaluronic acid (no warning about cancer or an infectious process in the body);
  • application after the procedure of abrasive skin care products, as well as acid peels;
  • use of decorative cosmetics until the damaged areas of the epidermis are completely healed;
  • visiting public bathing places in the first 2 weeks after the procedure;
  • the effect of heat on the treated area of ​​the skin (in a bath, sauna, hammam, etc.).

If you follow the doctor's recommendations and use hyaluronic acid only according to indications, unpleasant consequences from injections will not occur even after a few years. The use of drugs does not affect the possibility of getting pregnant, and also does not harm the hair. It does not enter the brain, therefore it is not the cause of pain in the head, even during the course of injections in the forehead in order to reduce wrinkles. The severity of side effects does not depend on gender and age - they can occur in both women and men.

Expert opinions

Oksana, professional experience 7 years:

Anyone can look good these days. Any woman over 25 years old can appreciate the benefits of hyaluronic acid. Over the years, I have noted several advantages of this method of rejuvenation: the absence of long-term side effects, the action is sufficient long term and the minimum number of contraindications. This is the safest way to stop old age that has ever existed.

Maria, professional experience 10 years:

I do not work as a cosmetologist, but as a surgeon, but I also use hyaluronic acid in clinical practice for my patients. We often prescribe intra-articular injection to increase the rate of tissue regeneration in patients. This is especially true in case of damage to the hip joint in older patients. Such injuries usually take a long time to heal, and thanks to our procedures, recovery is much easier and faster.

Olga, professional experience of 12 years:

The synthesis of hyaluronic acid is of great importance for cosmetology. Due to its high density, fillers from it have replaced plastic surgery for many people. This helps to avoid many of the unpleasant symptoms that occur after surgery. Therefore, there are so many rave reviews about her, including from my colleagues.

Answers on questions

How often can you get hyaluronic acid injections in your face?

How many injections are given depends on the type of drug used. There are funds that last for a year or more, and some for only 6-8 months. Therefore, when to start repeating the course is determined individually for each person by his cosmetologist.

Why can't hyaluronic acid preparations be used during antibiotic treatment?

The compatibility of hyaluronic acid with antibiotics is impossible due to obvious contradictions. Antibacterial agents are prescribed if there are signs of infection. And this condition is a contraindication to the administration of hyaluronic acid. It is possible to use drugs based on it only after stopping the disease.

Why is hyaluronic acid not used for cancer?

This substance stimulates the synthesis of new cells. But it affects all structures, including cancerous ones. This can lead to early metastasis and an increase in symptoms. At the same time, the patient's condition will worsen, and the risk of death will increase markedly.

Why is it dangerous to use for autoimmune diseases?

Autoimmune diseases occur when the body responds to its own organs. The antibodies produced by the person himself seek to destroy his cells. If, at the same time, a foreign substance is introduced, it will worsen the patient's condition, and new unexpected reactions will occur. Later effects include the progression of the underlying pathology with the further development of the body's allergic reaction to other organs and tissues.

Why can't you inject hyaluronic acid during lactation?

During lactation hormonal background the body changes significantly, which can be the reason for unexpected reactions to the introduction of any drugs. Studies of the effect of hyaluronic acid on women during breastfeeding have not been carried out, since it is prohibited by law. Therefore, scientists cannot be responsible for the fact that the components of the drugs do not enter the milk ducts with the blood stream. Because of this, the use of medicines and other drugs during this period is sharply limited.

Summing up

The introduction of hyaluronic acid has obvious benefits, although it can harm the body under certain conditions, including non-compliance with contraindications for use.

If you have been treated with this substance or are using home remedies, please share with us your results and impressions of these preparations.

Hyaluronic acid injections used in modern cosmetology, that is, intradermal hyaluronic injections, are considered sufficient in an efficient way partial getting rid of some defects in appearance, for example, from wrinkles on the face.

But before deciding on such a procedure, it will be useful to know: what is hyaluronic acid, due to which it smoothes the skin, are there any contraindications, what will the face be after the procedure? We will try to answer all your questions, including: are hyaluronic acid injections harmful?

Hyaluronic acid injections - to maintain the extracellular matrix

The principle of the effect of kraosta injections on the skin is compensatory, that is, an insufficient amount of endogenous hyaluronic acid synthesized by fibroblasts is replenished.

The connective tissue in our body has an interstitial (extracellular) space - the so-called extracellular matrix (Latin matrix - base), which is a collection of extracellular molecules that provide structural and biochemical support to the surrounding cells. This base consists of complex proteins - glycoproteins (collagen, elastin, fibronectin, etc.), proteoglycans (linear carbohydrate-protein biopolymers), as well as linear polysaccharides with a negative charge associated with the protein part of the proteoglycans - glycosaminoglycans.

Glycosaminoglycans - along with chondroitin sulfates and keratan sulfates (which are part of the cartilage tissue, synovial fluid of the joints and tissue of the cornea of ​​the eyes) - also includes hyaluronic acid (or hyaluronan).

Hyaluronic acid is a high molecular weight acidic carbohydrate in the form of a specific polysaccharide that is located on the basement membranes of cells and moves during biosynthesis. Unfortunately, this substance is biodegradable: for example, in skin tissues, its half-life does not exceed 24 hours.

The hyaluronic acid molecule, which has a very high molecular weight, is one of the most hydrophilic (moisture-loving) molecules in nature and can bind water molecules in a volume that is almost a thousand times its own weight. Being in the extracellular matrix, it endows tissues with the ability to resist compression: it absorbs a significant amount of water, takes on a gel-like form and provides a counter-swelling force. In addition, it ensures the free passage of nutrients.

Due to its high viscosity, hyaluronic acid, which is part of the cartilage tissue and synovial fluid of the periarticular capsules, protects our joints from excessive wear and tear. Hyaluronic acid is also present in the tendons and ligaments, is contained in the vitreous humor of the eye (and maintains normal intraocular pressure).

In the skin, it is most of all in the basal layer of the epidermis, where proliferating keratinocytes are located, as well as between the fibers of elastin and collagen. It is also present in the cells of the stratum corneum. Hyaluronic acid maintains optimal moisture levels in the skin by binding to water, thereby preventing elastin and collagen from drying out, which support the skin's structure.

Over time, that is, with age, the natural synthesis of hyaluronic acid gradually decreases, the skin retains less water and becomes dry. Beauty injections help the skin's extracellular matrix maintain adequate moisture levels.

By the way, the synthesis of hyaluronic acid almost completely stops at high doses of ultraviolet radiation, which is why the abuse of tanning dries and ages the skin ...

Hyaluronic acid injections for the face

Today, no one makes injections of hyaluronic acid for the face with the substance that was first obtained from chicken combs and bovine cartilage.

Currently, youth injections are made exclusively by its synthetic analogs, which are produced using modern biotechnology. This is sodium hyaluronate - the sodium salt of hyaluronic acid. In addition, pharmaceutical companies produce preparations based on this substance in the form of filler gels. At the same time, biochemists by means of "polymer crosslinking" have learned to reduce the length of the polysaccharide chain and its molecular weight - for better penetration into the skin structures and slowing down the process of its biological decay, that is, with a prolonged positive effect. Such hyaluronic acid is called structurally modified or stabilized.

The most famous preparations of hyaluronic acid for cosmetic needs: Juvederm (USA), Restylane and Restylane-L (USA), Esthelis (Switzerland), Elevess (USA), Princess (Austria), Hylaform (USA), Surgiderm (France), Yvoire ( France), Teosyal (Switzerland), Belotero (Switzerland), Perlane (USA), Puragen (UK). Some of these drugs contain anesthetics.

Hyaluronic acid injections for the face can increase the firmness and elasticity of the skin, smooth mimic wrinkles and, naturally, improve appearance. This method received the name "biorevitalization".

Beauty injections in cosmetology are also called "hyaluronic mesotherapy", taking the main principle of this technique: intradermal administration medicines in small doses. Although in this case this is not a treatment, but an injection method for correcting the face and its contours: wrinkles in the area of ​​the nasolabial folds, on the forehead, chin, and around the eyes. Sodium hyaluronate gel preparations (called fillers) are injected shallowly into the skin in the right places.

The face after injections of hyaluronic acid will look younger in a week or two, and the skin will look more elastic. But it should be borne in mind that correction with the use of hyaluronic acid gives a temporary effect, since all drugs with this substance dissolve over time. So, the rejuvenating effect of biorevitalization lasts no more than six months (or even less), and the maximum duration is 9-12 months. Therefore, the desire to look younger and more attractive will have to be reinforced by periodic repetition of this procedure.

Most women give lip injections with hyaluronic acid to make them look plump. The skin on the lips consists mainly of connective tissue and its components - hyaluronic acid and collagen, which give the lips their shape and plumpness. Hyaluronic acid, by binding water, creates a gel-like liquid that moisturizes the surrounding tissues and preserves collagen. And this is the main secret of plump lips after this procedure. At the same time, it is very important to strictly adhere to the dosage of the administered drugs - a maximum of 1.5 ml for each lip. Exceeding this dose is fraught with local reactions in the form of hyperemia and itching of the skin in the mouth area, as well as a violation of the natural shape of the lips due to the uneven distribution of the drug. But the most common reaction is swelling after injections of hyaluronic acid in the lips. In the absence of aggravating circumstances, redness, swelling and traces of youth injections disappear after a few days.

And injections of hyaluronic acid under the eyes are considered an effective (albeit temporary) way to remove chronic "bruises" in the area of ​​the eye sockets. However, after such a procedure, unwanted side effects often occur on such a delicate area of ​​the facial skin (more on this later).

Hyaluronic acid injections into the joints

They are used in orthopedics and rheumatology to compensate for the lack of synovial fluid in the joint capsule and increase its viscosity in order to improve the condition of synovial cartilage in arthritis and osteoarthritis of the knee and hip joints, as well as in other joint pathologies of a degenerative-dystrophic nature.

Hyaluronic acid injections into the joints - 1% sodium hyaluronate solution - are usually given once a week, the procedure is repeated three times. In clinical practice, for the treatment of joints, drugs such as Synvisc (USA), Sinokrom (Austria), Hi-Flex (Korea), Gialgan (Hyalgan Fidia Farmaceutici, Italy), etc. are used.

As noted by orthopedic doctors, injections make intra-articular lubrication in the synovial cavity of the joints more viscous. This restores its shock-absorbing properties, significantly improves the sliding of the articular cartilage, protects them from damage, and also helps relieve inflammation and pain.

Harm

The harm from the injection of hyaluronic acid is denied by some, and in vain.

Firstly, if a person has an innate tendency to autoimmune skin reactions (which he may not even be aware of), then as a result of beauty injections, they can trigger the development of lichen planus, systemic lupus erythematosus or psoriasis.

Secondly, being an important component of the extracellular matrix, the hyaluron takes Active participation in the division (proliferation) of cells, including cells of neoplasms. Studies have shown that the level of hyaluronic acid in tumor tissues is significantly higher than in normal tissues. So the injection of youth can cause the appearance of benign neoplasms in the form of fibrous nodes or thickening of subcutaneous adipose tissue.

Finally, beauty injections, temporarily increasing its content in the extracellular matrix, can lead to an increase in the synthesis of hyaluronidase, an enzyme that accelerates the decomposition of hyaluronic acid by hydrolysis. This enzyme breaks down all glycosaminoglycans and thereby cleans the extracellular matrix, including those tissues that are around the malignant tumor. Why is it dangerous? The fact that hydrolysis of hyaluronic acid on the basement membranes of vascular tissue cells (under the action of hyaluronidase) promotes intravasation - the penetration of cancer cells into the blood and lymphatic vessels.

Contraindications

Despite the specifics of the use of these drugs, there are serious contraindications to hyaluronic acid injections. These include:

  • hypersensitivity to the components of drugs with sodium hyaluronate;
  • abrasions, cuts, hematomas and any other damage, as well as foci of inflammation on the skin or in the subcutaneous tissue of the area of ​​the proposed injection;
  • fungal diseases of the skin of the face;
  • previous skin surgery or cosmetic procedures to exfoliate the stratum corneum (peeling);
  • increased body temperature;
  • any infectious diseases, including ARVI and influenza;
  • autoimmune dermatological diseases (psoriasis, atopic dermatitis, etc.); psoriasis);
  • keloid disease (genetically determined tendency to form keloid scars on the skin);
  • low blood clotting (including after the use of thrombolytics, anticoagulants or platelet inhibitors in the previous three weeks);
  • pregnancy and lactation;
  • age under 18;
  • deep wrinkles in old age.

They have a number of contraindications and injections of hyaluronic acid into the joints:

  • diseases of the joints of an inflammatory nature (rheumatoid arthritis, arthrosis, idiopathic spondylitis, etc.);
  • skin infection, damage or inflammation of the skin at the injection site;
  • liver failure (severe);
  • exacerbation of any chronic diseases;
  • venous or lymphatic congestion on the side of the affected joint;
  • taking immunosuppressive drugs (to suppress unwanted immune reactions of the body);
  • poor blood clotting;
  • pregnancy and lactation.

Consequences

Without the strictest adherence to the rules of asepsis and antisepsis, injections of youth, like any other procedure with violation of the skin, can be accompanied by the introduction of infectious agents into the tissues. This is fraught with skin abscesses and necrosis. Also, painful sensations almost always occur at the injection site.

The consequences of hyaluronic acid injections can have the form of side effects, namely:

  • an allergic reaction;
  • swelling of soft tissues of varying intensity in the area of ​​the performed procedure;
  • redness of the skin (hyperemia), often with itchy skin;
  • the appearance of papules (nodular rash);
  • bleeding at the injection site and local circulatory disorders (if the needle enters a blood vessel);
  • the appearance of a hematoma (bruise);
  • the occurrence of a keloid scar at the injection site;
  • wrinkling of the skin;
  • hyperpigmentation of the skin in the area of ​​the injection;
  • activation of herpes in patients with a history of herpetic eruptions.

The consequences associated with an excessive amount of the injected drug are expressed in the fact that it is displaced from the injection site.

Clinical observations indicate that injections of youth can significantly harm health.

Hyaluronic acid (hyaluronate, HA) is a naturally occurring polysaccharide found in the body of any mammal. In the human body, acid is contained in the lens of the eye, cartilage tissue, joint fluid and in the intercellular space of the skin.

For the first time, the German biochemist Karl Meyer spoke about hyaluronic acid in 1934, when he discovered it in the lens of a cow's eye. The new substance was investigated. In 2009, the British journal International Journal of Toxicology issued an official statement: hyaluronic acid and its derivatives are safe to use. Since then, hyaluronate has been used in medicine and cosmetology.

Hyaluronic acid comes in two types of origin:

  • animal (obtained from the combs of roosters);
  • non-animal (synthesis of bacteria that produce HA).

In cosmetology, synthetic hyaluronate is used.

Hyaluronic acid is also divided into two types in terms of molecular weight - nixomolecular and high molecular weight. The difference lies in function and effect.

Low molecular weight HA is used for superficial application to the skin. This provides deep hydration, penetration of active substances and the formation of enzymes that protect the skin surface from harmful effects.

The high molecular weight composition is used for injection. It smoothes deep wrinkles, improves skin tone, and removes toxins. There is no strict differentiation of HA for invasive (subcutaneous) or superficial use. Therefore, cosmetologists use hyaluronate of both types in practice.

What is hyaluronic acid for?

Many are interested in why hyaluronic acid is needed and why it is popular.

Hyaluronic acid got widespread due to its "absorbent" properties. One hyaluronate molecule holds 500 water molecules. Hyaluronic acid molecules enter the intercellular space of the skin and hold back water, preventing evaporation. This ability of the acid retains water in the body for a long time and maintains the moisture level in the tissues constantly. There is no longer a substance with a similar ability.

Hyaluronic acid plays important role in preserving the beauty and youth of the face. Hyaluronate is responsible for density, elasticity and moisture maintenance. With age, the body decreases the amount of HA produced, which leads to skin aging. In an effort to slow down skin aging, women use hyaluronic acid for their face.

Useful properties of hyaluronic acid

The beauty benefits of hyaluronic acid are undeniable: it tightens and tones the skin of the face, controlling the amount of moisture in the cells. Let's highlight other positive properties:

  • eliminates the appearance of acne, pigmentation;
  • improves skin color;
  • quickly heals burns and cuts;
  • smoothes scars, evens out skin relief;
  • returns elasticity.

Means for external use

An affordable option for using hyaluronate is cosmetic products that contain acid. Fixed HA products are face creams, masks, and serums that can be purchased at a pharmacy or store. The first and second options for funds can be prepared independently at home. For home "production" use hyaluronic acid powder: it is easier to measure and more convenient to store. You can apply the finished product pointwise (on problem areas) or on the entire surface of the skin. The duration of the course is 10-15 applications. The frequency of use is selected individually.